American Society for Clinical Pathology (ASCP) Technologist in Cytogenetics certification (ASCP CG) Practice Test

How many bands are observed on chromosome 10 in the 425 to 475 band level range?

1. 12 to 15

2. 15 to 21

3. 20 to 25

4. 18 to 22

The correct answer is: 15 to 21

The correct range for the number of bands observed on chromosome 10 in the 425 to 475 band level range is indeed 15 to 21. Each chromosome is divided into specific regions and further categorized into bands that highlight variations in the chromatin structure, allowing for the identification of different genetic loci. In the case of chromosome 10, this banding pattern is particularly important for genetic mapping and identifying chromosomal abnormalities. Detailed analysis of the euchromatin and heterochromatin distribution on chromosome 10 reveals this particular band density. The banding technique, often utilized through G-banding or other staining methods, shows the visibility of the bands, which number between 15 to 21 in the specified range. This knowledge is crucial for cytogenetics technologists who work in the field, as it aids in the diagnosis of genetic disorders and the study of chromosomal behaviors during cell division. Understanding the typical banding patterns can also assist in identifying structural alterations in the chromosome that may be linked to specific diseases or conditions.