American Society for Clinical Pathology (ASCP) Technologist in Cytogenetics certification (ASCP CG) Practice Test

In the 500 to 550 band level range, how many bands are typically present on chromosome 10?

1. 18 to 20

2. 20 to 24

3. 22 to 28

4. 25 to 30

The correct answer is: 22 to 28

In the context of cytogenetics, the banding of chromosomes refers to the distinct regions that can be visualized under a microscope after staining. Each band corresponds to a specific segment of the chromosome, allowing for the identification of chromosomal abnormalities. For chromosome 10, the typical number of bands in the 500 to 550 band level range is defined based on the karyotype nomenclature system. In this range, approximately 22 to 28 bands represent the expected number found on chromosome 10 when visualized under normal conditions. This is crucial for identifying chromosomal structures and potential abnormalities linked to various genetic disorders. The identified bands correspond to specific genes and loci that can be assessed for rearrangements or mutations, making this information vital for diagnostic and research purposes in cytogenetics. Thus, the correct answer reflects the standard characterization within this band range for chromosome 10 and serves as a benchmark for cytogenetic analysis.