American Society for Clinical Pathology (ASCP) Technologist in Cytogenetics certification (ASCP CG) Practice Test

What is needed to confirm the chromosome number of a suspected overlapping chromosome in a karyotype?

1. Only the ID number of the patient

2. A description of the cell type

3. What laboratory performed the analysis

4. ID number, scope used, and coordinates of the met

The correct answer is: ID number, scope used, and coordinates of the met

To confirm the chromosome number of a suspected overlapping chromosome in a karyotype, one must identify specific details such as the ID number, the scope used, and the coordinates of the metaphase. The ID number is essential to ensure that the analysis corresponds to the correct patient sample, enabling traceability and proper verification. The scope used provides insight into the magnification and resolution capabilities during observation, which can affect the ability to discern overlapping or subtler chromosomal features. Finally, the coordinates of the metaphase are crucial because they indicate the specific position of the chromosomes during analysis, allowing for precise identification and confirmation of any abnormalities present. The other options do not provide a comprehensive approach necessary for confirming chromosome numbers in this context. Having only the ID number or a description of the cell type lacks the detailed information required for analysis and may lead to ambiguity in interpreting karyotypic data. Similarly, knowing which laboratory performed the analysis does not contribute directly to confirming the chromosome number; it may provide context but does not aid in the actual identification process.